Therapeutic Monoclonal Antibodies

Course Description & Information:

  • It was only 45 years ago that monoclonal antibody (mAb) technology was created. In the last 35 years, use of therapeutic monoclonal antibodies has grown from a benchtop dream, which resulted in the first approved therapeutic monoclonal antibody, to a rapidly expanding drug branch, with more than 80 approved products. Today, there is an ever-expanding number of diseases where therapeutic mAbs or their fragments offer viable alternative therapeutic choices to traditional drug treatments. Many patients find disease relief or cure for conditions which are difficult to effectively treat with traditional pharmacologic agents. This presentation will address the development of therapeutic mAbs, some of their current applications, and insights into potential future therapies.
  • Pharmacist information: ACPE UAN: 0826-9999-19-022-L01-P, IRD: 6-13-19. Knowledge based activity.
Course Objectives:

  • State what an antibody is.
  • Explain what monoclonal antibodies are, and the traditional method of their creation.
  • Differentiate among murine, chimeric, humanized and human monoclonal antibodies.
  • Compare mechanisms by which selected monoclonal antibodies (or fragments) improve disease responses.
  • Evaluate how therapeutic monoclonal antibodies (or fragments) can be integrated into traditional treatments, for selected diseases.
  • Summarize potential advantages and disadvantages of selected therapeutic monoclonal antibodies.


Course Credit: 2 Contact Hours

Accreditations: View Course Accreditations

Who Should Attend:

Pharmacists, Dietitians, and Nursing professionals (2 hours of pharmacotherapeutic credit).

Certificate Requirements:

  • Full attendance.
  • Completion of course post-test (70%) and evaluation.

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